Research Overview

Public Health

Public health research

Transportation

Transportation

Agent Network

Network of collaborating agents

More Applications

Tools for additional applications

Civilized & Engineered AI Copilot

AI copilot
  • Domain Adaptation
  • Grounded Reasoning
  • Trustworthy AI
  • Decision Support
  • Prompt Optimization

Human-AI Value Alignment

AI copilot Human perspectives
  • Human Priors
  • Personalized Modeling
  • Interpretable Reasoning
  • Sequential Reasoning

Efficient and Sustainable Intelligence Scaling

Multiple AI agents Human perspectives
  • Mixture of Experts
  • Adaptive Computing
  • Efficient Inference
  • Edge Intelligence
  • Resource Efficiency

AI for Decision Making

Large language models are becoming decision interfaces for complex systems, but reliable decisions still require domain grounding, uncertainty awareness, and actionable intervention design. We develop decision-making methods that use LLMs to connect data, language, and optimization, enabling applications such as public health analysis, personalized decision modeling, and trustworthy traffic safety assessment.

Agentic AI for Tool Use and Collaborative Intelligence

LLMs are powerful collaborators, but their reasoning becomes more reliable when it is shaped by human priors, physical constraints, and domain knowledge. Our work on collaborative intelligence studies how LLMs can organize, evaluate, and improve their own reasoning through self-governance, and how LLM-based mixture-of-experts systems can coordinate specialized agents to produce grounded, cooperative intelligence.

Sustainable Computing and Intelligence Scaling

Scaling LLMs and multimodal foundation models is not only about making models larger; it also requires efficient computation, adaptive routing, and deployable intelligence under real-world resource constraints. We design computing and intelligence scaling methods for energy and transportation systems, edge AI, computing efficiency, and LLM life assessment that bring large-model intelligence closer to practical deployment.

Advancing real-time infectious disease forecasting using large language models
2025

Advancing real-time infectious disease forecasting using large language models

Hongru Du, Yang Zhao, Jianan Zhao, Shaochong Xu, Xihong Lin, Yiran Chen, Lauren M. Gardner, Hao Frank Yang

Nature Computational Science

Domain Adaptation Decision Support Public Health [PDF] [DOI]
Personalized Decision Modeling: Utility Optimization or Textualized-Symbolic Reasoning
2025

Personalized Decision Modeling: Utility Optimization or Textualized-Symbolic Reasoning

Yibo Zhao, Yang Zhao, Hongru Du, Hao Frank Yang

Advances in Neural Information Processing Systems (NeurIPS), 2025 Spotlight

Sequential Reasoning Personalized Modeling Interpretable Reasoning Public Health Transportation [PDF] [DOI]
How to Auto-optimize Prompts for Domain Tasks? Adaptive Prompting and Reasoning through Evolutionary Domain Knowledge Adaptation
2025

How to Auto-optimize Prompts for Domain Tasks? Adaptive Prompting and Reasoning through Evolutionary Domain Knowledge Adaptation

Yang Zhao, Pu Wang, Hao Frank Yang

Advances in Neural Information Processing Systems (NeurIPS), 2025

Prompt Optimization Domain Adaptation Grounded Reasoning Efficient Inference [PDF] [DOI]
SafeTraffic Copilot: adapting large language models for trustworthy traffic safety assessments and decision interventions
2025

SafeTraffic Copilot: adapting large language models for trustworthy traffic safety assessments and decision interventions

Yang Zhao, Pu Wang, Yibo Zhao, Hongru Du, Hao Frank Yang

Nature Communications volume 16, Article number: 8846 (2025)

Trustworthy AI Interpretable Reasoning Decision Support Transportation [PDF] [DOI]
Toward Optimal Mixture of Experts System for 3D Object Detection: A Game of Accuracy, Efficiency and Adaptivity
2025

Toward Optimal Mixture of Experts System for 3D Object Detection: A Game of Accuracy, Efficiency and Adaptivity

Linshen Liu, Pu Wang, Guanlin Wu, Junyue Jiang, Hao Frank Yang

IEEE Transactions on Pattern Analysis and Machine Intelligence (TPAMI)

Resource Efficiency Mixture of Experts Adaptive Computing Efficient Inference Transportation [PDF] [DOI]
Towards Accurate and Efficient 3D Object Detection for Autonomous Driving: A Mixture of Experts Computing System on Edge
2025

Towards Accurate and Efficient 3D Object Detection for Autonomous Driving: A Mixture of Experts Computing System on Edge

Linshen Liu*, Boyan Su*, Junyue Jiang, Guanlin Wu, Cong Guo, Ceyu Xu, Hao Frank Yang†

International Conference on Computer Vision (ICCV), Poster

Resource Efficiency Mixture of Experts Edge Intelligence Efficient Inference Transportation [PDF] [DOI]
Towards Physics-informed Spatial Intelligence with Human Priors: An Autonomous Driving Pilot Study
2025

Towards Physics-informed Spatial Intelligence with Human Priors: An Autonomous Driving Pilot Study

Guanlin Wu*, Boyan Su*, Yang Zhao, Pu Wang, Yichen Lin, Hao Frank Yang†

Advances in Neural Information Processing Systems (NeurIPS), 2025 Spotlight

Grounded Reasoning Human Priors Transportation [PDF] [DOI]
Cost-effective vehicle recognition system in challenging environment empowered by micro-pulse lidar and edge AI
2024

Cost-effective vehicle recognition system in challenging environment empowered by micro-pulse lidar and edge AI

Junyue Jiang, Hongliang Lu, Chenxi Liu, Meixin Zhu, Yiran Chen, Hao Frank Yang

2024 IEEE Intelligent Vehicles Symposium (IV)

Resource Efficiency Edge Intelligence Efficient Inference Transportation [PDF] [DOI]